From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors

MeSH terms

• Adenosine Triphosphate / pharmacology
• Binding Sites
• Cell Cycle Proteins / antagonists & inhibitors*
• Cell Cycle Proteins / chemistry
• Cell Cycle Proteins / metabolism
• Coloring Agents / chemical synthesis
• Coloring Agents / chemistry*
• Coloring Agents / pharmacology
• Cyclin-Dependent Kinase Inhibitor p21
• Indoles / chemical synthesis
• Indoles / chemistry*
• Indoles / pharmacology
• Models, Molecular
• Molecular Structure
• Protein Kinase Inhibitors / chemical synthesis*
• Protein Kinase Inhibitors / chemistry
• Protein Kinase Inhibitors / pharmacology*
• Protein Structure, Tertiary
• Solubility
• Sulfonamides / chemistry